The Antidepressant Food Score was designed to identify the most nutrient-dense individual foods to prevent and promote recovery from depressive disorders and symptoms. Results can be used to inform the design of future research studies or clinical dietary recommendations. This tool is based on a systematic literature review, evidence-informed list of Antidepressant Nutrients, and nutrient density calculation. The highest scoring animal foods were bivalves such as oysters and mussels, various seafoods, and organ meats. The highest scoring plant-based foods were leafy greens, lettuces, peppers, and cruciferous vegetables. These foods can be integrated into any dietary pattern.